Matrixyl 3000 is a synthetic compound that is created by combining two existing peptide groups, palmitoyl tetrapeptide-7 and palmitoyl oligopeptide, resulting in an entirely new peptide group. All of these peptides function in much the same way as Vitamin C, and in most cases they outperform naturally occurring versions of Vitamin C: they help your cells resist the damaging effects of Ultra-Violet radiation, strengthen your skin’s protective membranes and barriers, and promote the production of collagen (The structural supports that crisscross beneath your skin, making it firm).

At this time, there are no established studies that outline possible side effects of using Matrixyl 3000 in topical cosmetic products. Because there are no reliable studies on the topic, we would advise consumers to take care when purchasing products that include Matrixyl 3000 as an ingredient. Due to the functional similarities between Matrixyl 3000 and other compounds that promote collagen production, please consider the possibility that Matrixyl 3000 may have similar side effects to those products that contain other collagen-growth ingredients.

One point that should be mentioned is that all clinical studies concerning Matrixyl 3000 were all conducted in-house and were funded by the manufacturer. Although the product is touted as being “thoroughly subjected to clinical testing,” none of those studies were conducted by third-party research teams. For this reason, consumers should take any claims regarding this product’s “benefits” and any potential “side effects” with a grain of salt.

To find which products contain this ingredient, check out our wrinkle cream comparison chart.